Liangyu Tao presents poster at Minnesota Neuromodulation Symposium

Lianyu Tao, an undergraduate BME major, presented the following poster at the Minnesota Neuromodulation Symposium Apr 13-14.  This work is in collaboration with Helen Mayberg at Emory University, and also involves Rehman Ali (now a PhD student at Stanford, formerly a GT BME undergrad), and Vineet Tiruvadi (an MD/PhD student in Biomedical Engineering at Georgia Tech and Emory University).

Modeling Dynamic Oscillations in Deep Brain Stimulation of the Subcallosal Cingulate
Liangyu Tao1, Vineet Tiruvadi1,2, Rehman Ali3, Helen Mayberg2, Robert Butera1
1. Georgia Institute of Technology, USA; 2. Emory University, USA; 3. Stanford University, USA

new publication – IEEE Transactions on Neural Systems and Rehabilitation Engineering

Our lab’s paper below was recently accepted.  You can read a copy online here.

Y. A. Patel, B. S. Kim, W. S. Rountree, and R. J. Butera. “Kilohertz Electrical Stimulation Nerve Conduction Block: Effects of Electrode Surface Area.” (2017) IEEE Transactions on Neural Systems and Rehabilitation Engineering.  Accepted February, 2017.

Abstract

Kilohertz electrical stimulation (KES) induces repeatable and reversible conduction block of nerve activity and is a potential therapeutic option for various diseases and disorders resulting from pathological or undesired neurological activity. However successful translation of KES nerve block to clinical applications is stymied by many unknowns such as the relevance of the onset response, acceptable levels of waveform contamination, and optimal electrode characteristics. We investigated the role of electrode geometric surface area on the KES nerve block threshold using 20 and 40 kHz current-controlled sinusoidal KES. Electrodes were electrochemically characterized and used to characterize typical KES waveforms and electrode charge characteristics. KES nerve block amplitudes, onset duration, and recovery of normal conduction after delivery of KES were evaluated along with power requirements for effective KES nerve block. Results from this investigation demonstrate that increasing electrode geometric surface area provides for a more power efficient KES nerve block. Reductions in block threshold by increased electrode surface area were found to be KES frequency dependent, with block thresholds and average power consumption reduced by >2x with 20 kHz KES waveforms and >3x for 40 kHz KES waveforms.

 

Rehman Ali accepted to Stanford PhD Program

Congratulations to Rehman Ali, a BME undergraduate alumni of the lab, for his acceptance to the Stanford PhD program in Electrical Engineering!

 

Liangyu Tao receives President’s Undergraduate Research Travel Award

Liangu Tao, an undergraduate BME student in the lab, has received a Georgia Tech President’s Undergraduate Research Award to support travel to present a poster at the Minnesota Neuromodulation Symposium, to be held April 13-14, 2017, in Minneapolis.  His poster info is below:

Modeling Dynamic Oscillations in Deep Brain Stimulation of the Subcallosal Cingulate
Liangyu Tao1, Vineet Tiruvadi1,2, Rehman Ali3, Helen Mayberg2, Robert Butera1
1. Georgia Institute of Technology, USA; 2. Emory University, USA; 3. Stanford University, USA

Yogi Patel wins Bioengineering “Best Paper Award”

Yogi Patel has won the Georgia Tech Bioengineering Graduate Program’s Best Paper award!  Congratulations Yogi!

This is for the paper “Kilohertz frequency nerve block enhances anti-inflammatory effects of vagus nerve stimulation” published in Scientific Reports at http://www.nature.com/articles/srep39810